2006-2010

  1. "Omnipotent role of archaeal elongation factor 1 alpha (EF1α) in translational elongation and termination, and quality control of protein synthesis."
    Saito K, Kobayashi K, Wada M, Kikuno I, Takusagawa A, Mochizuki M, Uchiumi T, Ishitani R, Nureki O, Ito K,
    Proc Natl Acad Sci U S A., 107 19242-19247 (2010).
  2. "Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification."
    Kato M, Araiso Y, Noma A, Nagao A, Suzuki T, Ishitani R, Nureki O,
    Nucleic Acids Res., 39 1576-85 (2010).
  3. "Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex."
    Kobayashi K, Kikuno I, Kuroha K, Saito K, Ito K, Ishitani R, Inada T, Nureki O,
    Proc Natl Acad Sci U S A. , 107 17575-17579 (2010).
  4. "C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNASec."
    Sherrer RL, Araiso Y, Aldag C, Ishitani R, Ho JM, Söll D, Nureki O,
    Nucleic Acids Res., 39 1034-41 (2010).
  5. "Expanding role of the Jumonji C domain as an RNA hydroxylase."
    Noma A, Ishitani R, Kato M, Nagao A, Nureki O, Suzuki T,
    J Biol Chem., 285 34503-7 (2010).
  6. "Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation."
    Nureki O, O'Donoghue P, Watanabe N, Ohmori A, Oshikane H, Araiso Y, Sheppard K, S醇rll D, Ishitani R,
    Nucleic Acids Res., 38 7286-97 (2010).
  7. "Editing mechanism of aminoacyl-tRNA synthetases operates by a hybrid ribozyme/protein catalyst."
    Hagiwara Y, Field MJ, Nureki O, Tateno M,
    J Am Chem Soc. , 132 2751-2758 (2010).
  8. "Molecular mechanisms underlying the early stage of protein translocation through the Sec translocon."
    Mori T, Ishitani R, Tsukazaki T, Nureki O, Sugita Y,
    Biochemistry, 49 945-950 (2010).
  9. "Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase"
    Nakanishi K, Bonnefond L, Kimura S, Suzuki T, Ishitani R, Nureki O,
    Nature, 461 1144-1148 (2009).
  10. "Structure of a tRNA-dependent kinase essential for selenocysteine decoding"
    Araiso Y, Sherrer RL, Ishitani R, Ho JM, S�ll D, Nureki O,
    Proc Natl Acad Sci U S A, 106 16215-16220 (2009).
  11. "Mg2+-dependent gating of bacterial MgtE channel underlies Mg2+ homeostasis"
    Hattori M, Iwase N, Furuya N, Tanaka Y, Tsukazaki T, Ishitani R, Maguire ME, Ito K, Maturana A, Nureki O,
    EMBO J, 28 3602-3612 (2009).
  12. "Mechanism for the definition of elongation and termination by the class II CCA-adding enzyme."
    Toh Y, Takeshita D, Numata T, Fukai S, Nureki O, Tomita K.,
    EMBO J., 28 3353-3365 (2009).
  13. "Structural Basis of Novel Interactions Between the Small-GTPase and GDI-like Domains in Prokaryotic FeoB Iron Transporter."
    Hattori M, Jin Y, Nishimasu H, Tanaka Y, Mochizuki M, Uchiumi T, Ishitani R, Ito K, Nureki O.,
    Structure., 17 1345-55 (2009).
  14. "Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2."
    Umitsu M, Nishimasu H, Noma A, Suzuki T, Ishitani R, Nureki O.,
    Proc Natl Acad Sci U S A., 106 15616-21 (2009).
  15. "Crystallization and preliminary X-ray diffraction analysis of the truncated cytosolic domain of the iron transporter FeoB."
    Jin Y, Hattori M, Nisimasu H, Ishitani R, Nureki O.,
    Acta Crystallogr Sect F Struct Biol Cryst Commun., 65(Pt 8) 784-7 (2009).
  16. "Structural modelling of the complex of leucyl-tRNA synthetase and mis-aminoacylated tRNA(Leu)."
    Hagiwara Y, Nureki O, Tateno M.,
    FEBS Lett., [Epub ahead of print] (2009).
  17. "The structure of alanyl-tRNA synthetase with editing domain."
    Sokabe M, Ose T, Nakamura A, Tokunaga K, Nureki O, Yao M, Tanaka I.,
    Proc Natl Acad Sci U S A , 106 11028-11033 (2009).
  18. "Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases."
    Shirakawa R, Fukai S, Kawato M, Higashi T, Kondo H, Ikeda T, Nakayama E, Okawa K, Nureki O, Kimura T, Kita T, Horiuchi H.,
    J Biol Chem. , 284 21580-8 (2009).
  19. "Identification of the nucleophilic factors and the productive complex for the editing reaction by leucyl-tRNA synthetase."
    Hagiwara Y, Nureki O, Tateno M.,
    FEBS Lett, 583(12) 1901-8 (2009).
  20. "Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon."
    Osawa T, Ito K, Inanaga H, Nureki O, Tomita K, Numata T.,
    Structure, 17(5) 713-24. (2009).
  21. "Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein."
    Higuchi T, Hattori M, Tanaka Y, Ishitani R, Nureki O.,
    Proteins, 76(3) 768-71 (2009).
  22. "Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase."
    Nishimasu H, Ishitani R, Yamashita K, Iwashita C, Hirata A, Hori H, Nureki O,
    Proc Natl Acad Sci U S A, 106(20) 8180-5 (2009).
  23. "Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4."
    Suzuki Y, Noma A, Suzuki T, Ishitani R, Nureki O,
    Nucleic Acids Res., 37(9) 2910-25 (2009).
  24. "Pyrrolysyl-tRNA synthetase tRNAPyl structure reveals the molecular basis of orthogonality."
    Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Soll D and Nureki O,
    Nature, 457(7233) 1163-1167 (2009).
  25. "Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator."
    Seto A, Ikushima H, Suzuki T, Sato Y, Fukai S, Yuki K, Miyazawa K, Miyazono K, Ishitani R and Nureki O,
    Acta Crystallogr Sect. F Struct. Biol. Cryst. Commun., 65(Pt 1) 21-24 (2009).
  26. "Conformational transition of Sec machinery inferred from bacterial SecYE structures."
    Tsukazaki T, Mori H, Fukai S, Ishitani R, Mori T, Dohmae N, Perederina A, Sugita Y, Vassylyev D, Ito K and Nureki O,
    Nature, 455 988-991 (2008).
  27. "Mg2+-sensing mechanism of Mg2+ transporter MgtE probed by molecular dynamics study."
    Ishitani R, Sugita Y, Dohmae N, Furuya N, Hattori M and Nureki O.,
    Proc Natl Acad Sci U S A, 105(40) 15393-15398 (2008).
  28. "Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains."
    Sato Y, Yoshikawa A, Yamagata A, Mimura H, Yamashita M, Ookata K, Nureki O, Iwai K, Komada M and Fukai S.,
    Nature, 455 358-362 (2008).
  29. "Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme."
    Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O and Tomita K.,
    EMBO J., 27 1944-1952 (2008).
  30. "Structure, dynamics, and function of RNA modification enzymes."
    Ishitani R, Yokoyama S and Nureki O.,
    Curr Opin Struct Biol., 18(3) 330-339. (2008).
  31. "Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets."
    Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, Horiguchi M, Okuda T, Okawa K, Fukai S, Nureki O, Kita T and Horiuchi H.,
    J Biol Chem., 283(13) 8746-8755. (2008).
  32. "Regulation of Platelet Dense Granule Secretion by the Ral GTPase-Exocyst Pathway."
    Kawato M, Shirakawa R, Kondo H, Higashi T, Ikeda T, Okawa K, Fukai S, Nureki O, Kita T and Horiuchi H.,
    J. Biol. Chem., 283(1) 166-174 (2008).
  33. "Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation."
    Araiso Y, Palioura S, Ishitani R, Sherrer RL, O'Donoghue P, Yuan J, Oshikane H, Domae N, Defranco J, Soll D and Nureki O.,
    Nucleic Acids Res., 36(4) 1187-1199. (2008).
  34. "Use of layer silicate for protein crystallization: Effects of Micromica and chlorite powders in hanging drops."
    Takehara M, Ino K, Takakusagi Y, Oshikane H, Nureki O, Ebina T, Mizukami F and Sakaguchi K.,
    Anal. Biochem., 373(2) 322-329 (2008).
  35. "Animated crystallography of genetic code translation."
    Tomita K, Numata T, Fukai S, Ishitani R and Nureki O.,
    Nucleic Acids Symp. Ser. (Oxf), 51 101-102 (2007).
  36. "Crystal structure of human DAAM1 formin homology 2 domain."
    Yamashita M, Higashi T, Suetsugu S, Sato Y, Ikeda T, Shirakawa R, Kita T, Takenawa T, Horiuchi H, Fukai S and Nureki O.,
    Genes Cells., 12(11) 1255-65 (2007).
  37. "Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of a cation diffusion facilitator family protein."
    Hattori M, Tanaka Y, Ishitani R and Nureki O.,
    Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 63(Pt 9) 771-773 (2007).
  38. "Anticodon recognition and discrimination by the alpha-helix cage domain of class I lysyl-tRNA synthetase."
    Levengood JD, Roy H, Ishitani R, Söll D, Nureki O and Ibba M.,
    Biochemistry., 46(39) 11033-11038 (2007).
  39. "Crystal Structure of the Radical SAM Enzyme Catalyzing Tricyclic Modified Base Formation in tRNA."
    Suzuki Y, Noma A, Suzuki T, Senda M, Senda T, Ishitani R and Nureki O.,
    J. Mol. Biol., 372(5) 1204-1214 (2007).
  40. "Crystal structure of the MgtE Mg2+ transporter."
    Hattori M, Tanaka Y, Fukai S, Ishitani R and Nureki O.,
    Nature, 448 1072-1075 (2007).
  41. "Crystallization and preliminary X-ray diffraction analysis of the full-length Mg2+ transporter MgtE."
    Hattori M, Tanaka Y, Fukai S, Ishitani R and Nureki O.,
    Acta Crystallograph Sect F Struct Biol Cryst Commun. , 63(Pt 8) 682-684 (2007).
  42. "Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of the Mg2+ transporter MgtE."
    Tanaka Y, Hattori M, Fukai S, Ishitania R and Nureki O.,
    Acta Crystallograph Sect F Struct Biol Cryst Commun, 63(Pt 8) 678-681 (2007).
  43. "Crystal structure of the Sec4p·Sec2p complex in the nucleotide exchanging intermediate state "
    Sato Y, Fukai S, Ishitani R and Nureki O,
    PNAS, 104 (19) 8305-8310 (2007).
  44. "Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity."
    Sato Y, Shirakawa R, Horiuchi H, Dohmae N, Fukai S and Nureki O,
    Structure, 15 245-252 (2007).
  45. "Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog."
    Suto K, Shimizu Y, Watanabe K, Ueda T, Fukai S, Nureki O and Tomita K.,
    EMBO J., 24 5942-5950 (2006).
  46. "Complete crystallographic analysis of the dynamics of CCA sequence addition."
    Tomita K, Ishitani R, Fukai S and Nureki O.,
    Nature, 7114 956-960 (2006).
  47. "Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei."
    Yanagisawa T, Ishii R, Fukunaga R, Nureki O and Yokoyama S.,
    Acta Crystallograph Sect F Struct Biol Cryst Commun., Pt 10 1031-1033 (2006).
  48. "Functional categorization of the conserved basic amino acid residues in TrmH [tRNA (Gm18) methyltansferase] enzymes."
    Watanabe K, Nureki O, Fukai S, Endo Y and Hori H,
    J. Biol. Chem., 45 34630-34639 (2006).
  49. "Structural basis of RNA-dependent recruitment of glutamine to the genetic code"
    Oshikane H, Sheppard K, Fukai S, Nakamura Y, Ishitani R, Numata T, Sherrer RL, Feng L, Schmitt E, Panvert M, Blanquet S, Mechulam Y, Soll D and Nureki O.,
    Science, 312 1950-1954 (2006).
  50. "Snapshots of tRNA sulphuration via an adenylated intermediate"
    Numata T, Ikeuchi Y, Fukai S, Suzuki T and Nureki O.,
    Nature, 442 419-424 (2006).
  51. "Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus"
    Tsukazaki T, Mori H, Fukai S, Numata T, Perederina A, Adachi H, Matsumura H, Takano K, Murakami S, Inoue T, Mori Y, Sasaki T, Vassylyev DG, Nureki O and Ito K.,
    Acta Crystallographica, F., 62 376-380 (2006).
  52. "Crystallization and preliminary X-ray analysis of tRNA thiolation enzyme MnmA from Escherichia Coli complexed with tRNAGlu"
    Numata T, Ikeuchi Y, Fukai S, Adachi H, Matsumura H, Takano K, Murakami S, Inoue T, Mori Y, Sasaki T, Suzuki T and Nureki O.,
    Acta Crystallographica F., 62 368-371 (2006).
  53. "Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa"
    Sengoku T, Nureki O, Nakamura A, Kobayashi S and Yokoyama S.,
    Cell, 125 287-300 (2006).
  54. "Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex"
    Numata T, Fukai S, Ikeuchi Y, Suzuki T and Nureki O.,
    Structure, 14 357-366 (2006).